New child cancer drug tests successful - Houston Business Journal:

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The drug, AMD3100, was shown to reduc e the growth of a tumodr by more than 75 percentin mice, accordingv to investigators who presented their findingw Friday at the 22nd annual meeting of the in San “AMD3100 works by shuttingf down the process that tumors need to set up vasculaer systems,” Patrick Zweidler-McKay, senior investigator on the said in a statement. “The drug doesn’t kill neuroblastomz cells directly, but it prevents tumors from growing rapidlh by disrupting theirblood “There is the possibility that this therapy coule help prevent neuroblastoma metastasis to the bone However, more studies are needed to investigate this theory.
” Abougt 650 children in the United States under the age of five are diagnosed each year with according to the . Of those nearly two-thirds are diagnosed after the cancer has metastasized to other parts ofthe body. For thess patients with high-risk neuroblastoma, long-terkm survival is less than 40 percent becausr the tumors are often resistan totraditional chemotherapy.